Sermorelin (sermorelin acetate) is a drug whose only FDA-approved brand, Geref, has been discontinued; versions sold by clinics today are compounded and not FDA-approved.
What sermorelin costs
We could not confirm prices for compounded sermorelin for this page. Telehealth and men's health companies that list it, such as Maximus and Gameday Men's Health, did not show a sermorelin price on the pages we read [3] [4]. When comparing quotes, ask for the monthly total including the consult, labs, supplies and shipping, and whether you must commit to several months.
FDA status
Geref, made by EMD Serono, was approved by FDA on Sept 26 1997. Drugs@FDA lists its marketing status as discontinued [1]. No other sermorelin product is FDA-approved in our research.
Sermorelin is not on any of FDA's 503A bulk substance category lists, because it was a component of a previously approved drug rather than a nominated bulk substance [2]. Whether pharmacies may compound it can depend on why the brand left the market. We could not confirm FDA's determination on that question for this page.
Compounded sermorelin is not the same as Geref
Compounded drugs are not FDA-approved. FDA does not review them for safety, effectiveness or quality before they are sold. Compounded sermorelin is not a generic of Geref.
Where people get sermorelin online and in clinics
- Maximus lists sermorelin and growth hormone peptides. It received an FDA warning letter on June 8 2026 over compounded GLP-1 claims [5]. See our Maximus review.
- Gameday Men's Health, a franchise network of 400+ clinics, lists sermorelin among its peptides [4]. Its clinics are independently owned franchises, so ask each location which pharmacy it uses. See our Gameday review.
- Eden lists sermorelin. Its June 8 2026 FDA letter cited Eden branding on compounded labels [6]. See our Eden review.
- OrderlyMeds offers compounded sermorelin to current GLP-1 patients only and received an FDA warning letter on June 8 2026 [7]. See our OrderlyMeds review.
We do not link to sites selling peptides labeled for research use only. FDA has called such products unapproved new drugs in warning letters, including one to Peptide Partners in Aug 2026 [8].
Dosing and how-to questions
We do not give dosing, mixing or reconstitution instructions for compounded sermorelin. Units depend on the concentration printed on the pharmacy label. Follow your prescriber's instructions and the pharmacy label, and ask your pharmacist.
When to get help
Signs of an allergic reaction after an injection, such as hives, swelling of the face, lips or throat, or trouble breathing, need emergency care. Call 911.
Related peptides with stricter FDA findings
FDA's Category 2 list of bulk substances with significant safety concerns had six entries in May 2026, including ibutamoren mesylate and kisspeptin-10. Sermorelin was not on it [2].
Insurance
With the brand discontinued [1], sermorelin is sold as a cash-pay compounded product. Ask your HSA administrator before using HSA funds.
If you are looking at sermorelin for low energy or low testosterone, compare the FDA-approved routes in testosterone replacement therapy and online TRT clinics. More: wellness injections, NAD+ injections.
Questions people ask
How much does sermorelin cost?
Is sermorelin FDA-approved?
The brand Geref (sermorelin acetate) was approved on Sept 26 1997, and Drugs@FDA lists it as discontinued [1]. Sermorelin sold by clinics today is compounded and not FDA-approved.
Why was Geref discontinued?
Drugs@FDA lists Geref (NDA 020443) as discontinued [1]. We could not confirm FDA's determination of the reason.
Can I get sermorelin online?
Is sermorelin on FDA's list of dangerous compounding substances?
No. As of May 2026, sermorelin was not on any 503A category list, including Category 2 (significant safety concerns), which had six entries such as ibutamoren mesylate and kisspeptin-10 [2].
How many units of sermorelin should I take?
Units depend on the concentration printed on your pharmacy label. Follow your prescriber's instructions and the label, and ask your pharmacist. No sermorelin product is currently FDA-approved with a label dose, since Geref is discontinued [1].
Can I take sermorelin with tirzepatide?
Our research has no data on combining them. Ask your prescriber and pharmacist. Compounded sermorelin is not FDA-approved, and the only brand, Geref, is discontinued [1].
Sources
8 cited
- Drugs@FDA: Geref (sermorelin acetate), NDA 020443. US Food and Drug Administration, accessed 2026-10-17.
- Bulk drug substances nominated for use in compounding under section 503A (category lists). US Food and Drug Administration, May 14, 2026.
- Maximus home page. Maximus, accessed 2026-10-17.
- Gameday Men's Health. Gameday Men's Health, accessed 2026-10-17.
- Warning letter: Maximus Health Inc dba Maximus. US Food and Drug Administration, Jun 8, 2026.
- Warning letter: Eden Health International dba Eden. US Food and Drug Administration, Jun 8, 2026.
- Warning letter: OrderlyMeds LLC. US Food and Drug Administration, Jun 8, 2026.
- Warning letter: Peptide Partners LLC. US Food and Drug Administration, Aug 24, 2026.
This page is general information, not medical advice. Talk with a licensed clinician about your own care.